About NCHS

Research Projects

You can start making a difference today. Please go to www.worldcommunitygrid.org and become a member today and then join our team: NC Health.

In its first year, World Community Grid ran the Human Proteome Folding Project, which provided scientists with data on how individual proteins within the human body affect human health – important information that will help scientist develop cures for diseases like malaria and tuberculosis. Scientists now have descriptions of 120,000 protein domains that are critical to human well-being; without the benefit of this free grid technology, it would have taken 5 years to get these results, compared with just 12 months on World Community Grid. A second phase of this project is now under way, focusing on a small number of proteins, with a particular focus on proteins linked to malaria, that are key markers for disease diagnosis. View status report

On November 21, 2005 World Community Grid launched FightAIDS@Home. FightAIDS@Home, which is sponsored by The Scripps Research Institute, is using computational methods to identify new candidate drugs to block HIV protease, a key molecular structure that when blocked, stops the virus from maturing and thus is a way of avoiding the onset of AIDS and prolonging life. View status report

On July 20, 2006, World Community Grid launched an effort that will assist in cancer research using the massive computational power of World Community Grid. The Help Defeat Cancer project will use World Community Grid to analyze tissue microarrays (TMA) – a new investigative tool that will ultimately help doctors select proper treatments and provide accurate prognosis for cancer patients. View status report

In November 2006, World Community Grid launched The Genome Comparison Project, which will perform pair-wise comparisons among and between all genes for all sequenced organisms (from human beings to fruit flies to yeast) and build a database of the results. Because the database will be available to the research community, other scientists will have a huge headstart in understanding what these proteins do, how they play a role in disease processes, and ultimately in understanding how to devise a drug to combat a disease involved with the particular protein in question. View status report

In December 2006, World Community Grid launched Help Cure Muscular Dystrophy, a part of the Decrypthon program in France. In order to understand how proteins perform their necessary functions in living cells, a better and more detailed understanding of function and protein-protein interactions is required, to ultimately help researchers to design therapeutic strategies. Your contribution to this project will result in valuable information being made available for research that is part of the Decrypthon Program. Eventually your contribution will benefit all researchers working on genetic diseases, particularly, neuromuscular diseases. The ultimate hope is that we will help to develop innovative therapies that will lead to treatment for the vast majority of neuromuscular diseases, including Muscular Dystrophy. View project status

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